Both have some genetic component as their etiology, but lifestyle is also an important contributing factor. Both are associated with CV complications. Both can be managed by lifestyle modification. In selected cases, pharmacotherapy can be used for the treatment of obesity. When using drugs for the management of diabetes, attention should be paid to their side effects, since some of them can cause weight gain. Bariatric surgery is an effective treatment for both. Bariatric surgery can reduce CV complications and reduce total mortality.